食品科学 ›› 2010, Vol. 31 ›› Issue (11): 293-297.doi: 10.7506/spkx1002-6630-201011064

• 专题论述 • 上一篇    下一篇

真菌毒素性质及免疫原制备方法的研究进展

孙亚宁1 , 2,侯玉泽1 ,* ,邓瑞广2,胡骁飞2,王 磊1,赵丽娜1   

  1. 1.河南科技大学食品与生物工程学院 2.河南省农业科学院动物免疫重点实验室
  • 收稿日期:2009-11-02 出版日期:2010-06-01 发布日期:2010-12-29
  • 通讯作者: 侯玉泽 E-mail:happylsht@163.com
  • 基金资助:

    河南省基础与前沿技术研究重大项目(092300410028);“十一五”国家科技支撑计划项目(2006BAK02A21)

Current Advances in Characteristics of Fungaltoxin and Preparation of Antigen

SUN Ya-ning1,2,HOU Yu-ze1,*,DENG Rui-guang2,HU Xiao-fei2,WANG Lei1,ZHAO Li-na1,ZHI Ai-min2,LIU Qing-tang2,ZHANG Gai-ping2   

  1. 1. College of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471003, China;
    2. Henan Key Laboratory for Animal Immunology, Henan Academy of Agricultural Science, Zhengzhou 450002, China
  • Received:2009-11-02 Online:2010-06-01 Published:2010-12-29
  • Contact: HOU Yu-ze E-mail:happylsht@163.com

摘要:

真菌毒素是一些真菌在生长过程中所产生的毒性很强的次级代谢产物,通过食品或饲料危害动物和人类的健康及安全。能充分认识真菌毒素性质,准确快速的检测真菌毒素是控制其危害的最有效手段,现阶段酶联免疫(ELISA)检测方法已经成为真菌毒素快速检测的主要趋势,本文对一些主要真菌毒素的性质、种类、危害以及真菌毒素的ELISA 检测方法中重要环节——免疫原制备方法的研究做一综述。

关键词: 黄曲霉毒素, 赭曲霉毒素, 伏马菌素, 玉米赤霉烯酮, 脱氧雪腐镰刀菌烯醇, 免疫原制备方法

Abstract:

Fungaltoxins are secondary metabolites with strong toxicity during growth process of fungi. They are dangerous to human health and safety through food or feed chains. The most effective method to control its negative impact is to fully understand their characteristics for conducting accurate and rapid detection. Currently, ELISA detection method has become the major trend for rapid detection of mycotoxins. In this paper, the characteristics, classifications, harmfulness, preparation methods of immunogen and ELISA detection of fungaltoxins is reviewed.

Key words: aflatoxin, ochratoxin, fumonisin, zearalenone, deoxynivalenol, antigen preparation

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