食品科学

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邻苯二甲酸酯类暴露风险评估研究进展

鲍佳沁1,王 敏2,*,高 曦3,陈 波3,张 楠1,丁卓平1,*   

  1. 1.上海海洋大学食品学院,上海 201306;2.上海出入境检验检疫局,上海 200135;
    3.复旦大学公共卫生学院,公共卫生安全教育部重点实验室,上海 200032
  • 发布日期:2014-12-15

Progress in Risk Assessment of Human Phthalate Ester Exposure

BAO Jia-qin1, WANG Min2,*, GAO Xi3, CHEN Bo3, ZHANG Nan1, DING Zhuo-ping1,*   

  1. 1. College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China; 2. Shanghai Entry-Exit
    Inspection and Quarantine Bureau, Shanghai 200135, China; 3. Key Laboratory of Public Health Safety, Ministry of Education,
    School of Public Health, Fudan University, Shanghai 200032, China
  • Published:2014-12-15

摘要:

邻苯二甲酸酯类(phthalate esters,PAEs)是一类内分泌干扰物,具有生殖毒性。本文综述PAEs的暴露来源和人群暴露水平。主要阐述近年来国内外PAEs的暴露评估手段及风险评估模式。其中,采用生物监测手段的累积风险评估能全面反映多种PAEs暴露的累积效应对人群的可能健康风险,是未来的研究热点。

关键词: 邻苯二甲酸酯, 内分泌干扰物, 生物监测, 风险评估, 累积暴露, 危害指数

Abstract:

Phthalate esters (PAEs) are endocrine disrupting chemicals having reproductive toxicity. In this paper, the
exposure sources of PAEs and the human exposure levels are reviewed. Approaches to assess human PAE exposure and risk
assessment modes in recent years are described. Cumulative risk assessment based on bio-monitoring can completely reflect
the cumulative adverse effect of several PAEs on human health, which will become a hot topic in the future.

Key words: phthalate esters, endocrine disrupting chemicals, biomonitoring, risk assessment, cumulative exposure, harzard index (HI)

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