食品科学 ›› 2020, Vol. 41 ›› Issue (3): 305-313.doi: 10.7506/spkx1002-6630-20190125-330

• 专题论述 • 上一篇    下一篇

基于先进材料的适配体传感器在真菌毒素快速检测中的研究进展

王嫦嫦,马良,刘微,郭婷,谭红霞,张宇昊,周鸿媛,陈露,李道亮   

  1. (1.西南大学食品科学学院,重庆 400715;2.武汉市农业科学院环境与安全研究所,湖北 武汉 430207;3.西南大学前沿交叉学科研究院生物学研究中心,重庆 400715)
  • 出版日期:2020-02-15 发布日期:2020-02-26
  • 基金资助:
    重庆市技术创新与应用示范项目(cstc2018jscx-msybX0204);重庆市留学归国人员创新创业计划项目(cx2018032); 中央高校基本科研业务费专项资金项目(SWU118088) 重庆市技术创新与应用示范项目(cstc2018jscx-msybX0204);重庆市留学归国人员创新创业计划项目(cx2018032); 中央高校基本科研业务费专项资金项目(SWU118088)

Advances in Aptasensors Based on Smart Materials for Rapid Detection of Mycotoxins

WANG Changchang, MA Liang, LIU Wei, GUO Ting, TAN Hongxia, ZHANG Yuhao, ZHOU Hongyuan, CHEN Lu, LI Daoliang   

  1. (1. College of Food Science, Southwest University, Chongqing 400715, China; 2. Institute of Environment and Safety, Wuhan Academy of Agricultural Science, Wuhan 430207, China; 3. Biological Science Research Center of Academy for Advanced Interdisciplinary Studies, Southwest University, Chongqing 400715, China)
  • Online:2020-02-15 Published:2020-02-26

摘要: 研究开发基于金纳米粒子、石墨烯和石墨烯纳米复合物、量子点等先进材料的适配体传感器并将其用于真菌毒素检测是近年来真菌毒素检测领域新兴的热点和趋势之一。将先进材料优异的光学性能、机械性能和导电性能与适配体传感器相结合,大幅提高了真菌毒素检测的灵敏度并扩大了选择性。本文概括了近10 年来文献报道的主要真菌毒素适配体序列,并对基于先进材料的适配体传感器在真菌毒素快速检测中的应用、现阶段存在的主要问题进行了分析和综述,以期为真菌毒素检测相关研究的开展提供参考和启发。

关键词: 适配体, 真菌毒素, 传感器, 先进材料, 快速检测

Abstract: Research of aptasensors based on advanced materials such as Au nanoparticles (AuNPs), graphene and graphene nanocomposites, and quantum dots (QDs) for the quick detection of mycotoxins is one of the emerging hotspots and trends in the field of mycotoxin detection in recent years. The superior optical, mechanical and electrical properties of advanced materials combined with aptasensors greatly increase the sensitivity and selectivity of mycotoxin detection. This paper summarizes the aptamer sequences of major mycotoxins reported in the literature in the last decade, and reviews the application of aptasensors based on advanced materials in rapid detection of mycotoxins. The main existing problems are also proposed. We hope that this review could provide the basis and inspiration for the development of mycotoxin detection methods.

Key words: aptamers, mycotoxins, sensor, advanced materials, rapid detection

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