食品科学 ›› 2022, Vol. 43 ›› Issue (23): 277-286.doi: 10.7506/spkx1002-6630-20211213-146

• 专题论述 • 上一篇    下一篇

单核细胞增生李斯特菌生物被膜交叉污染评估进展

王真,方太松,王园,赵婕秀,李卓思,秦晓杰,王 翔,董庆利   

  1. (1.上海理工大学健康科学与工程学院,上海 200093;2.上海中侨职业技术大学食品药品学院,上海 201514)
  • 出版日期:2022-12-15 发布日期:2022-12-28
  • 基金资助:
    国家自然科学基金青年科学基金项目(32102095); 上海市农委2021年度上海市科技兴农技术创新项目(X2021-02-08-00-12-F00782)

Progress in Cross-Contamination Assessment of Listeria monocytogenes Biofilm

WANG Zhen, FANG Taisong, WANG Yuan, ZHAO Jiexiu, LI Zhuosi, QIN Xiaojie, WANG Xiang, DONG Qingli   

  1. (1. School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China; 2. College of Food and Drug, Shanghai Zhongqiao Vocational and Technical University, Shanghai 201514, China)
  • Online:2022-12-15 Published:2022-12-28

摘要: 单核细胞增生李斯特菌(Listeria monocytogenes)(以下简称单增李斯特菌)是一种引发李斯特菌病罹患者高住院率和高死亡率的食源性致病菌,其可在冷、热、干燥和消毒剂处理等不利条件下黏附于食品接触表面并进一步形成难以清除的生物被膜。交叉污染是单增李斯特菌传播的主要途径,生物被膜的形成提高了单增李斯特菌在工厂和厨房环境持续传播和污染的可能性,可引发相关食源性疾病暴发和食品召回等,从而造成健康和经济损失。本文首先介绍了单增李斯特菌生物被膜的胞外聚合物组分,并从外部生存环境和内部微生物自身因素两方面总结了影响单增李斯特菌生物被膜交叉污染转移的因素;进一步重点从研究类型和细菌收集两方面阐述了生物被膜交叉污染的相关研究进展;最后,归纳总结了针对单增李斯特菌生物被膜形成早期的防控策略,展望该领域的研究前景,以期为科学评估和早期精准防控单增李斯特菌生物被膜交叉污染的潜在风险提供理论依据。

关键词: 单增李斯特菌;生物被膜;交叉污染;防控措施

Abstract: Listeria monocytogenes (L. monocytogenes) is a food-borne pathogen causing listeriosis, a sickness with high hospitalization rate and high mortality rate, and it can adhere to food contact surfaces under various adverse conditions such as cold, heat, dryness and disinfectant to form biofilms that are hard to remove. Cross-contamination is the major transmission route of L. monocytogenes, and biofilm formation increases the possibility of persistent transmission and contamination of L. monocytogenes in factory and kitchen environments, which may lead to the outbreak of food-borne diseases and food recalls, causing health and economic loss. In this article, the extracellular polymeric components of L. monocytogenes biofilms are introduced, and the internal and external factors affecting the cross-contamination and transfer of L. monocytogenes biofilms are summarized. A particular focus is placed on the recent progress in research on 、L. monocytogenes cross-contamination from the perspectives of research type and bacterial collection. In addition, we summarizes the prevention and control strategies for L. monocytogenes in the early stage of biofilm formation. Finally, the future prospects of this research field are proposed. We hope that this review could provide a theoretical basis for the scientific evaluation and accurate early prevention and control of the potential risk of L. monocytogenes biofilm cross-contamination.

Key words: Listeria monocytogenes; biofilm; cross-contamination; prevention and control measures

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