食品科学 ›› 2025, Vol. 46 ›› Issue (19): 28-36.doi: 10.7506/spkx1002-6630-20250307-058

• 基础研究 • 上一篇    

玉米醇溶蛋白-亚麻籽胶复合纳米颗粒的制备与表征:形成机理、理化稳定性

罗德云,王小晶,王希望,李丽,李永才   

  1. (甘肃农业大学食品科学与工程学院,甘肃 兰州 730070)
  • 发布日期:2025-09-16
  • 基金资助:
    “十四五”国家重点研发计划重点专项(2021YFD2100502-3); 甘肃农业大学博士科研启动项目(GAU-KYOD-2021-21)

Preparation and Characterization of Zein-Flaxseed Gum Composite Nanoparticles: Formation Mechanism and Physicochemical Stability

LUO Deyun, WANG Xiaojing, WANG Xiwang, LI Li, LI Yongcai   

  1. (College of Food Science and Engineering, Gansu Agricultural University, Lanzhou 730070, China)
  • Published:2025-09-16

摘要: 以玉米醇溶蛋白(zein)为基材,亚麻籽胶(flaxseed gum,FG)为壁材,采用反溶剂沉淀法制备了复合纳米颗粒zein-FG。结果表明,zein和FG添加量分别为20 mg/mL和0.2 mg/mL时,所形成的纳米颗粒zein-FG最稳定和均一,且其粒径为81.98 nm,多分散指数为0.25,Zeta电位为-37.69 mV。傅里叶变换红外光谱分析表明,氢键、静电相互作用和疏水作用是zein-FG形成的主要驱动力;X射线衍射分析揭示了FG与zein之间存在相互作用。此外,FG的加入改善了单一zein纳米颗粒的盐离子、pH值和贮藏稳定性。综上所述,zein-FG有潜力成为开发高效纳米递送系统的新材料。

关键词: 玉米醇溶蛋白;纳米颗粒;亚麻籽胶

Abstract: This study utilized zein as the core material and flaxseed gum (FG) as the coating material to prepare composite nanoparticles via the anti-solvent precipitation method. The results demonstrated that the nanoparticles prepared with 20 mg/mL zein and 0.2 mg/mL FG exhibited the best stability and uniformity, with a particle size of 81.98 nm, polydispersity index (PDI) of 0.25, and zeta potential of –37.69 mV. Fourier transform infrared spectroscopy (FTIR) analysis indicated that hydrogen bonding, electrostatic interactions, and hydrophobic interactions were the primary driving forces for zein-FG formation. X-ray diffraction (XRD) analysis revealed the presence of interactions between FG and zein. Furthermore, the incorporation of FG into zein nanoparticles enhanced its salt ion, pH, and storage stability. In conclusion, zein-FG nanoparticles show potential as novel materials for developing high-efficiency nanodelivery systems.

Key words: zein; nanoparticles; flaxseed gum

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