食品科学 ›› 2005, Vol. 26 ›› Issue (9): 446-450.

• 营养卫生 • 上一篇    下一篇

发酵乳抗高血压特性的研究

 吴玲, 潘道东   

  1. 南京师范大学生命科学学院,南京师范大学金陵女子学院食品科学与营养系
  • 出版日期:2005-09-15 发布日期:2011-09-20

Study on Antihypertensive Characterization of Yogurt

 WU  Ling, PAN  Dao-Dong   

  1. 1.Life Science College of Nanjing Normal University; 2.Food Science and Nutrition Department of Ginling Women’s College, Nanjing Normal University
  • Online:2005-09-15 Published:2011-09-20

摘要: 本研究通过抑制ACE活性实验,筛选出能发酵脱脂牛乳产生较强抗ACE活性的LacobacillushelveticusATCC15019、15009和LactobacillusthermophilusATCC14485三种乳酸菌菌株,用这三种菌株混合制作的发酵乳对ACE的活性具有较强的抑制作用。分别给原发性高血压大鼠连续三天灌胃此发酵乳和其乳清,结果发现它们都具有较强的降高血压作用,最大降压值分别为24.10±2.69mmHg和29.14±3.07mmHg,与对照组相比,呈极显著性差异(p<0.01)。

关键词: 发酵乳, ACE, 抗高血压

Abstract: The angiotensin-I-converting enzyme (ACE) inhibitory activity of f yogurt fermented with four lactic acid bacteria was investigated. The results found that the yogurt fermented with L. helveticus ATCC15019, 15009 and L. thermophilus ATCC14485 had the potent inhibitory activity on ACE. After the oral administration of the yogurt or its whey to spontaneously hypertensive rats (SHR) for three days, results showed that both of them had the antihypertensive effect, with the most decrease value of 24.10±2.69mmHg and 29.14±3.07mmHg of systolic blood pressure(SBP), which showed outstanding differences, compared with the control groups.

Key words: fermented milk (Yogurt), angiotensin-I-converting enzyme (ACE), antihypertensive