食品科学 ›› 2005, Vol. 26 ›› Issue (9): 509-510.

• 营养卫生 • 上一篇    下一篇

黑桑椹对高脂血症大鼠的降脂作用研究

 杨小兰, 毛立新, 张晓云   

  1. 山西大学生命科学与技术学院生物工程系,山西医科大学第一医院
  • 出版日期:2005-09-15 发布日期:2011-09-20

Hypolipidemic Effects of Black Mulberry Dried Fruit on Diet-induced Hyperlipidemia in Rats

 YANG  Xiao-Lan, MAO  Li-Xin, ZHANG  Xiao-Yun   

  1. 1.College of Life Science and Technologe, Shanxi University; 2.First Hospitol Medical College Shanxi
  • Online:2005-09-15 Published:2011-09-20

摘要: 目的研究黑桑椹对高脂血症大鼠脂质代谢的影响。方法普通基础饲料加10%猪油、1%胆固醇,0.5%胆酸钠组成高脂饲料。高脂饲料中添加10%的黑桑椹果粉饲喂Wistar大鼠(桑葚组),4w后与单饲高脂饲料的大鼠(高脂组)对比血脂和肝脂水平。结果与高脂组比较,桑葚组大鼠血清和肝脏的胆固醇、甘油三酯含量均显著降低(p<0.01),血清低密度脂蛋白胆固醇和致动脉硬化指数也明显下降(p<0.01),而高密度脂蛋白胆固醇和抗动脉硬化指数显著升高(p<0.01);结论黑桑椹果粉对高脂血症大鼠具有显著的降脂、抗动脉粥样硬化作用。

关键词: 黑桑椹, 血脂, 肝脂, 动脉粥样硬化, 大鼠

Abstract: Objective To investigate the effect of Black Mulberry Fruit(Morus alba L.) on lipia metabolism in rats fed high- fat diet. Methods Wistar rats were randomly divided into 3 groups and fed on basal diet, high-fat diet (basal diet with 10% lard and 1% cholesterol), test diet (high-fat diet with 10% black mulberry dried fruit) for 4 weeks. Results The results showed for hyperlipidemia rats, the high-fat diet with10% black mulberry dried fruit l can markedly decrease the serum TC、TG、LDL- c、 AI and liver TC、TG, meanwhile can increase serum HDL-c and AAI. Conclusion Black mulberry dried fruit has effects on hypolipidemic and anti-atherosolerosis.

Key words: black mulberry dried Fruit, serum lipid, Liver lipid, atherosclerosis, rat