食品科学 ›› 2005, Vol. 26 ›› Issue (9): 531-533.

• 营养卫生 • 上一篇    下一篇

大豆黄酮对机体疲劳应激下抗氧化能力的影响

 江芸, 高峰   

  1. 南京师范大学金陵女子学院食品科学系,南京农业大学动物科技学院
  • 出版日期:2005-09-15 发布日期:2011-09-20

Effect of Daidzein on Anti-oxidative Ability of Body under Fatigue-Stress 

 JIANG  Yun, GAO  Feng   

  1. 1.Department of Food Science, Ginling College, Nanjing Normal University; 2.College of Animal Science and Technology, Nanjing Agricultural University
  • Online:2005-09-15 Published:2011-09-20

摘要: 以26名健康大学生志愿者为受试对象,采用逐级递增负荷疲劳运动方式,研究大豆黄酮对机体疲劳应激下抗氧化能力的影响。结果显示,疲劳运动后人体血清CAT、SOD酶活性有所增加,而GSH-Px酶活性显著升高(p<0.05),血清MDA含量有所升高;服用大豆黄酮后进行疲劳应激,三种抗氧化酶活性均升高,且均稍高于对照组应激后水平,其中GSH-Px活性显著高于服用前(p<0.05),SOD活性极显著高于服用前(p<0.01),显著高于服用后(p<0.05),MDA含量几乎没有较多变化,且与对照组应激后水平相比有所降低。结果表明,大豆黄酮能明显增强应激机体的抗氧化能力,减少应激机体的自由基产生,具有一定的抗应激效应。

关键词: 大豆黄酮, 疲劳应激, 抗氧化酶, 丙二醛

Abstract: 26 healthy volunteer undergraduates were selected to observe the anti-oxidative effect of daidzein under fatigue-stress, with the method of the gradual-loading-exercise. The results showed that, after exercising, the activities of CAT, GSH-Px, SOD and the content of MDA in the control group increased, and the change of the activity of GSH-Px was significant (p<0.05). In the daidzein group, the activities of three kinds of anti-oxidases all increased after exercising, and were higher than those of the control group. The activities of GSH-Px and SOD after exercising increased significantly compared with those before taking daidzein (p<0.05 or p<0.01) and the activity of SOD increased significantly compared with that after taking daidzein (p< 0.05). The content of MDA of the daidzein group increased little after exercising, and was lower than that of the control group. These results indicated that daidzein could improve the anti-oxidative ability and reduce the level of MDA under fatigue-stress and thus enhance the anti-stress ability.

Key words: daidzein, fatigue stress, anti-oxidase, malondialdehyde ( MDA )