食品科学 ›› 2006, Vol. 27 ›› Issue (1): 226-230.
• 营养卫生 • 上一篇 下一篇
龚晨睿, 潘思轶
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GONG Chen-Rui, PAN Si-Yi
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摘要: 评价特异性鸡蛋黄抗体作为保健食品素材的食用安全性。采用急性毒性试验、小鼠骨髓微核试验、小鼠精子畸形试验、Ames试验和30d喂养试验进行检测。结果表明:雌、雄小鼠急性经口LD50>20ml/kg体重,属无毒级;小鼠骨髓微核试验、精子畸形试验和Ames试验结果均为阴性;30d喂养试验未显示明显毒性。
关键词:  , 鸡蛋黄抗体, 急性毒性, 遗传毒性, 喂养试验
Abstract: To evaluate the edible safety of prepared IgY. Some tests of acute oral toxicity, born marrow cell micronucleus, sperm shape abnormality in mice, Ames and thirty - day feeding were conducted in our study.The LD50 of all the rats and mice were more than 20ml/ kg bw, so the teeth protection spray belonged to actually non - toxicity; tests of born marrow cell micronucleus, sperm shape abnormality in mice, Ames were negative; The thirty - day feeding test in rats demonstrated that it had no distinctive effects on routine blood, body weight and biochemical index. The teeth protection spray was safe for edibility.
Key words: IgY, acute toxicity, heredity toxicity, thirty- day feeding
龚晨睿, 潘思轶. 特异性鸡蛋黄抗体的毒理学安全性研究[J]. 食品科学, 2006, 27(1): 226-230.
GONG Chen-Rui, PAN Si-Yi. Toxicological Assessment on Prepared IgY Safety[J]. FOOD SCIENCE, 2006, 27(1): 226-230.
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