食品科学 ›› 2007, Vol. 28 ›› Issue (10): 585-589.

• 专题论述 • 上一篇    下一篇

利用海洋生物蛋白制备ACE抑制肽的研究进展

 刘立闯, 胡志和, 贾嘉   

  1. 天津市食品生物技术重点实验室天津商业大学生物技术与食品科学学院; 天津市食品生物技术重点实验室天津商业大学生物技术与食品科学学院 天津300134; 天津300134;
  • 出版日期:2007-10-15 发布日期:2011-11-22

Research Advance of Preparation of ACE Inhibitory Peptides Derived from Marine Proteins

 LIU  Li-Chuang, HU  Zhi-He, JIA  Jia   

  1. Tianjin Key Laboratory of Food Biotechnology, College of Biotecnology and Food Science, Tianjin University of Commerce, Tianjin 300134, China
  • Online:2007-10-15 Published:2011-11-22

摘要: 血管紧张素转化酶(angiotensin convert enzyme,ACE)在血压调节方面起着重要作用,当其受到抑制时血压就会降低。本文综述了A C E抑制肽的降压原理、活性检测方法、分离提纯和海洋生物蛋白源A C E抑制肽的国内外最新研究进展,并对其应用前景进行了展望。

关键词: 海洋生物蛋白, ACE抑制肽, 抑制活性, 高血压

Abstract: Angiotensin convert enzyme (ACE) plays an important physiologic role in the blood pressure regulation. Specific inhibition effects of ACE have shown itself to be useful as antihypertensive drugs. The paper reviewed the antihypertensive principle, separation and purification, activity determination methods and the latest domestic and international research progress of the ACE inhibitory peptides, and their wide developmental prospects were forecasted.

Key words: marine protein, ACE inhibitory peptide, inhibitory activity, hypertension