食品科学 ›› 2007, Vol. 28 ›› Issue (2): 369-372.

• 专题论述 • 上一篇    下一篇

微生物发酵生产乳链菌肽的分离技术研究进展

 吉玉强, 吴兆亮, 郭雅楠, 于广和   

  1. 河北工业大学生物工程系; 天津康益生物技术有限公司 天津300130; 天津300130; 天津301801;
  • 出版日期:2007-02-15 发布日期:2011-12-31

Review on Nisin Separation Technology from Fermentation Broth

 JI  Yu-Qiang, WU  Zhao-Liang, GUO  Ya-Nan, YU  Guang-He   

  1. 1.Department of Bioengineering, Hebei University of Technology, Tianjin 300130, China; 2.Kangyi Co. Ltd., of Biological Technique, Tianjin 301801, China
  • Online:2007-02-15 Published:2011-12-31

摘要: 乳链菌肽(nisin)是一种由乳链球菌产生的乳酸菌素,为一种天然生物防腐剂,广泛应用于食品工业中。目前,文献报道中有关乳链菌肽的分离纯化方法很多,但是否适合工业化生产有待于进一步研究。本文在评述微生物发酵生产乳链菌肽过程中分离纯化技术基础上,分析了其难于实现工业生产的原因并提出了需要解决的问题。

关键词: 乳链菌肽, 分离, 进展

Abstract: Nisin is a bacteriocin produced by Lactococcus. It is widely used as a safe and natural food preservative in food industry. At present, there are a lot of purification and separation methods about nisin in the literature, but whether they are suitable for industrialization needs to be further studied. On the basis of reviewing the present technology for extraction and purification of nisin after fermentation, this paper analysed the difficulties for industrialization of these methods, and envisaged the future development.

Key words: nisin, separation, development