食品科学 ›› 2008, Vol. 29 ›› Issue (11): 692-695.

• 专题论述 • 上一篇    下一篇

L-苹果酸的生理功能研究进展

 吴军林, 吴清平, 张菊梅   

  1. 广东省微生物研究所广东省菌种保藏与应用重点实验室;
  • 出版日期:2008-11-15 发布日期:2011-12-08

Research Progress of Physiological Functions of L-malate

 WU  Jun-Lin, WU  Qing-Ping, ZHANG  Ju-Mei   

  1. Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application,Guangdong Institute of Microbiology,Guangzhou 510070,China
  • Online:2008-11-15 Published:2011-12-08

摘要: L-苹果酸是生物体代谢过程中产生的重要有机酸,在线粒体产生能量物质ATP的代谢过程中起到重要作用。苹果酸是苹果酸天冬氨酸穿梭的重要组成部分,对胞液和线粒体之间的还原当量(NADH)的转移起重要的作用。因此,L-苹果酸在机体内具有重要的代谢意义,同时具有显著的生理功能。能够有效的提高运动能力,具有抗疲劳、保护心脏、促进羧酸盐的代谢、促进线粒体呼吸、改善记忆能力、增强钙的活性、降低抗癌药物毒副作用等生理功能。

关键词: L-苹果酸, 苹果酸天冬氨酸穿梭, 生理功能

Abstract: L-malate,an important organic acid in the process of metabolism,plays an important role in generating mitochondria ATP.Moreover,L-malate is a component of malate-aspartate shuttle and is of importance in transporting NADH from cytosol to mitochondria for energy production.Therefore,L-malate is endowed with many physiological functions such as enhancing capacity of excises,anti-fatigue,protecting heart,increasing metabolism of carboxylates,improving respiration of mitochondria,increasing activity of calcium and reducing toxicity of anti-cancer medicament.

Key words: L-malate, malate-aspartate shuttle, physiological function