食品科学 ›› 2008, Vol. 29 ›› Issue (8): 636-639.

• 专题论述 • 上一篇    下一篇

2-酮基-D-葡萄糖酸发酵生产研究进展

魏转, 余泗莲, 孙文敬, 周强,李中兵   

  1. 河北化工医药职业技术学院制药工程系; 百勤异VC钠有限公司
  • 出版日期:2008-08-15 发布日期:2011-08-26

Research Progress on Fermentation Prcduction of 2-Keto-D-gluconic Acid

 WEI  Zhuan, YU  Si-Lian, SUN  Wen-Jing, ZHOU  Qiang, LI  Zhong-Bing   

  1. 1.Department of Pharmaceutical,Hebei Chemical and Pharmaceutical College,Shijiazhuang 050026,China;2.Parchn Sodium Isovitamin C Co. Ltd.,Dexing 334221,China;3.College of Food and Biological Engineering,Jiangsu University,Zhenjiang 212013,China
  • Online:2008-08-15 Published:2011-08-26

摘要: 2-酮基-D-葡萄糖酸(2KGA)是合成食品抗氧化剂D-异抗坏血酸钠及D-异抗坏血酸的前体,通常采用细菌发酵的方法由D-葡萄糖转化而来。本文概述了2KGA的生物合成途径、2KGA产生菌的选育、2KGA的发酵条件、2KGA的发酵工艺、2KGA发酵产物的提取、国内2KGA发酵生产中存在的主要问题及改善对策等。

关键词: 2-酮基-D-葡萄糖酸, 发酵, D-异抗坏血酸钠, D-异抗坏血酸

Abstract: 2-Keto-D-gluconic acid(2KGA),usually prepared by fermentative oxidation of D-glucose,is the precursor used in the manufacture of sodium erythorbate or erythorbic acid as a food antioxidant. The paper summarizes the biosynthesis pathway of 2KGA,breeding of 2KGA producing strains,fermentation conditions of the strains producing 2KGA,technology of 2KGA fermentation,isolation and purification of the fermentation product,the main problems and corresponding solutions of the domestic 2KGA fermentation production.

Key words: 2-keto-D-gluconic acid, fermentation, sodium erythorbate, erythorbic acid