食品科学 ›› 2009, Vol. 30 ›› Issue (23): 415-418.doi: 10.7506/spkx1002-6300-200923093

• 营养卫生 • 上一篇    下一篇

电子自旋共振研究银杏叶提取物对训练大鼠不同类型肌纤维自由基作用

李文建1 , 2,杨则宜3,曹远林4,陈宗道1 ,*   

  1. 1.西南大学食品科学学院 2. 国家体育总局体质评价与运动机能监控重点实验室 3.国家体育总局运动医学研究所 4.中国科学院生物物理研究所
  • 收稿日期:2008-12-23 出版日期:2009-12-01 发布日期:2010-12-29
  • 通讯作者: 陈宗道 E-mail:chenzongdao@swu.edu.cn
  • 基金资助:

    国家科技攻关计划奥运科技专项项目(2002BA904B16)

Effect of Ginkgo Biloba Extract on Free Radicals in Different Fiber Types of Rat Quadriceps by Electron Spin Resonance

LI Wen-jian1,2,YANG Ze-yi3,CAO Yuan-lin4,CHEN Zong-dao1,*   

  1. 1. College of Food Science, Southwest University, Chongqing 400716, China;2. Key Laboratory of Physical Fitness Assessment
    and Sport Performance Supervision, General Administration of Sport of China, Chongqing 400015, China;
    3. Institute of Sport Medicine, General Administration of Sport of China, Beijing 100100, China;
    4. Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
  • Received:2008-12-23 Online:2009-12-01 Published:2010-12-29
  • Contact: CHEN Zong-dao E-mail:chenzongdao@swu.edu.cn

摘要:

用电子自旋共振(ESR)方法研究银杏叶提取物(GBE)对训练大鼠不同类型肌纤维自由基的作用。结果表明,GBE 使训练大鼠白肌自由基(gQ=2.0050)显著增强(P < 0.05),红肌减弱(P=0.06);使训练大鼠运动力竭后即刻白肌自由基降低74.48%(P < 0.005),混合肌降低46.25%(P < 0.005),力竭后24h 时红肌、混合肌均明显增强(P < 0.05)。结果表明:GBE 主要促进训练大鼠红肌自由基清除,增强白肌代谢及抗氧化能力,抑制大鼠超强度运动白肌自由基产生,从而延迟运动性疲劳发生。

关键词: E SR, 银杏叶提取物, 训练大鼠, 力竭性运动, 股四头肌, 白肌, 红肌, 自由基

Abstract:

This study was aiming to investigate the effects of Ginkgo biloba extract (GBE) on free radicals of different fibre types of quadriceps in rats by electron spin resonance (ESR). Results showed that GBE suspension was able to significantly enhance the intensities of free radical signals (gQ=2.0050) in white muscle of exercise rats (P<0.05) while the decrease was observed in red muscles decreased (P=0.06). However, the intensity was decreased by 74.48% in white muscle (P<0.005) and by 46.25% in whole quadriceps (P<0.005) at instant while it was elevated remarkably in red muscle (P<0.05) and whole quadriceps (P<0.05) after 24h of strenuous exhaustive exercise. The results showed that GBE could accelerate clearance of free radicals in red muscle and enhance the anti-oxidant activity and exercise tolerance of white muscles.

Key words: ESR, ginkgo biloba extract, exercise rats, exhaustive exercise, quadriceps, white muscle, red muscle, free radicals

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