食品科学 ›› 2024, Vol. 45 ›› Issue (17): 242-252.doi: 10.7506/spkx1002-6630-20230722-252

• 专题论述 • 上一篇    下一篇

海藻酸盐纳米载体递送亲脂性活性物质及其应用研究进展

徐薇, 李慧雪, 刘霄莹, 孙亚鹏, 张润峰, 陈山   

  1. (广西大学轻工与食品工程学院,广西 南宁 530004)
  • 出版日期:2024-09-15 发布日期:2024-09-09
  • 基金资助:
    国家自然科学基金地区科学基金项目(32260561);广西研究生教育创新计划资助项目(YCSW2024066)

Research Progress on Alginate Nanocarrier Delivery of Lipophilic Active Substances and Its Application

XU Wei, LI Huixue, LIU Xiaoying, SUN Yapeng, ZHANG Runfeng, CHEN Shan   

  1. (College of Light Industry and Food Engineering, Guangxi University, Nanning 530004, China)
  • Online:2024-09-15 Published:2024-09-09

摘要: 亲脂性活性物质因其天然优势和潜在的功能特性备受食品和保健品领域关注,然而其存在疏水性和对环境(如氧气、光、温度)敏感的缺陷,摄食后会在消化道环境中部分或完全降解,难以被人体有效吸收和利用。利用稳定性强且具有屏障效应的海藻酸盐纳米递送载体可有效解决上述问题并延长亲脂性活性物质释放时间。本文综述海藻酸盐的结构及其凝胶性、pH值响应性和生物学活性等功能特性,重点介绍海藻酸盐纳米载体,如纳米乳液、纳米颗粒、纳米凝胶、纳米纤维递送亲脂性活性物质的研究现状及不同纳米载体类型的优缺点,并对其在食品领域应用现状进行总结,旨在为亲脂性活性物质在食品领域的应用提供参考。

关键词: 海藻酸盐;纳米载体;亲脂性活性物质;应用

Abstract: Lipophilic active substances are of great interest to the field of food and health products because of their natural advantages and potential functional properties. However, they are difficult to effectively digest and absorb in the human body due to their hydrophobicity, environmental sensitivity deficiencies (such as oxygen, light, temperature) and partial or complete degradation in the digestive tract after ingestion. Using alginate nano-delivery carriers with strong stability and barrier effect can effectively solve the above problems while prolonging the release of lipophilic active substances. This paper reviews the structure of alginate and its functional properties such as gelation properties, pH response and biological activity, with a focus on the current status of research on alginate nanocarriers, such as nanoemulsions, nanoparticles, nanogels and nanofibers for the delivery of lipophilic active substances as well as the advantages and disadvantages of different nanocarriers. Finally, this article summarizes the application status of alginate in the food field, aiming to provide a reference for the application of lipophilic active substances in the food field.

Key words: alginate; nanocarrier; lipophilic active substances; application

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