食品科学 ›› 2025, Vol. 46 ›› Issue (17): 299-277.doi: 10.7506/spkx1002-6630-20250120-148

• 专题论述 • 上一篇    

微藻破壁处理技术、生物活性及应用研究进展

龚韧,金虎,李海岭,李雅洁,杨海麟   

  1. (1.江南大学生物工程学院,江苏?无锡 214122;2.山东天骄生物技术股份有限公司,山东?菏泽 274108;3.中国科学院水生生物研究所,湖北?武汉 430072;4.延边大学农学院,吉林?延边 133002;5.江南大学生物工程学院,工业生物技术教育部重点实验室,江苏?无锡 214122)
  • 发布日期:2025-08-18
  • 基金资助:
    国家自然科学基金面上项目(21776113;21878128);“十四五”国家重点研发计划重点专项(2022YFC3401300); 泰山产业领军人才项目(tscx202306112)

Research Progress on Microalgae: Cell Disruption Technologies, Bioactivity and Application

GONG Ren, JIN Hu, LI Hailing, LI Yajie, YANG Hailin   

  1. (1. School of Biotechnology, Jiangnan University, Wuxi 214122, China; 2. Shandong Tianjiao Biotechnology Co. Ltd., Heze 274108, China; 3. Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China; 4. Agriculture College of Yanbian University, Yanbian 133002, China; 5. Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China)
  • Published:2025-08-18

摘要: 微藻作为一种高效、可持续的生物资源,以其独特的代谢机制和丰富的功能性成分(如蛋白质、不饱和脂肪酸、色素、多糖和多酚类化合物)在食品、医药、化妆品等领域展现出广泛的应用潜力。本文探讨微藻破壁处理技术,详细讨论机械破壁法、物理破壁法、化学破壁法、酶解破壁法及联合破壁法的最新研究进展及其对成分提取效率的影响。同时总结微藻功能性成分的主要生物活性,包括抗氧化、抗菌、免疫调节、降血脂、抗糖尿病及抗肿瘤作用,并阐述其在健康促进与疾病干预中的作用机制。此外,梳理微藻资源在食品、药品及化妆品领域的实际应用现状,分析其在产业化过程中的技术挑战与不足之处。未来,通过优化提取工艺、深入研究生物活性机制以及推动多领域应用的产业化,微藻功能性资源将为健康产业和可持续发展提供更多支持。本综述可为微藻资源的开发与多领域应用提供理论依据和实践指导。

关键词: 微藻;提取;破壁;生物活性;应用

Abstract: Microalgae, as an efficient and sustainable biological resource, have demonstrated great potential for application in various fields such as food, medicine, and cosmetics due to their unique metabolic mechanisms and abundant functional components including proteins, unsaturated fatty acids, pigments, polysaccharides, and polyphenolic compounds. This review explores the latest advances in cell disruption techniques for the extraction of functional components from microalgae with a special focus on mechanical, physical, chemical, enzymatic, and combined methods, as well as their effects on the extraction efficiency. The major bioactivities of microalgal functional components including antioxidant, antimicrobial, immunomodulatory, lipid-lowering, antidiabetic, and anticancer properties are summarized along with their mechanisms of action in health promotion and disease intervention. Furthermore, the current status of the application of microalgae resources in the food, pharmaceutical, and cosmetic industries is reviewed, and the technical challenges and limitations of their industrialization are analyzed. Optimizing the extraction process, delving deeper into the mechanisms of the bioactivities, and promoting industrial applications across multiple sectors will enable microalgal functional resources to provide greater support for the health industry and sustainable development. This article offers a theoretical foundation and practical guidance for the development and multifaceted application of microalgae resources.

Key words: microalgae; extraction; cell disruption; bioactivity; application

中图分类号: