食品科学 ›› 2026, Vol. 47 ›› Issue (2): 386-397.doi: 10.7506/spkx1002-6630-20250722-179

• 专题论述 • 上一篇    

蛋黄卵磷脂的研究进展:提取鉴定、功效活性及应用

刘嘉贤,阚启鑫,胡伟,周亮,耿鹏飞,曹庸   

  1. (1.华南农业大学食品学院,广东省功能食品活性物重点实验室,广东 广州 510642;2.武汉市米来生物科技有限公司,湖北 武汉 430014)
  • 出版日期:2026-01-25 发布日期:2026-02-05
  • 基金资助:
    广东省功能食品活性物重点实验室项目(2018B030322010)

Advances in Research on Egg Yolk Lecithin: Extraction, Identification, Bioactivities and Applications

LIU Jiaxian, KAN Qixin, HU Wei, ZHOU Liang, GENG Pengfei, CAO Yong   

  1. (1. Key Laboratory of Nutraceuticals and Functional Foods of Guangdong Province, College of Food Science, South China Agricultural University, Guangzhou 510642, China; 2. Wuhan Milai Biotechnology Co., Ltd., Wuhan 430014, China)
  • Online:2026-01-25 Published:2026-02-05

摘要: 蛋黄卵磷脂是一种天然的动物源磷脂复合物,主要由磷脂酰胆碱、磷脂酰乙醇胺、鞘磷脂、溶血磷脂酰胆碱、溶血磷脂酰乙醇胺等组分构成,具有保护神经、护肝、抗衰老、免疫调节等多重功效活性。利用溶剂法、超临界萃取、膜分离、柱层析等技术能有效从蛋黄中分离提取出卵磷脂,后续联合质谱分析和脂质组学能够实现对蛋黄卵磷脂的精准解析。另外,蛋黄卵磷脂是一种独特的两亲性物质,含有亲水端的磷酸基团-极性头基和疏水端的脂肪酸链,能形成双分子层囊泡结构,常用于包埋易敏活性物质或小分子药物,可有效提高目标包埋物的生物利用度。蛋黄卵磷脂的应用范畴不断从传统的食品领域拓展至高附加值的药品、保健品、化妆品领域,展现出巨大的开发潜力。因此,本文系统全面地梳理了蛋黄卵磷脂的结构特性、提取鉴定方法、功效活性及其在不同领域的应用,以期能对其未来的研究和高值化应用提供理论参考。

关键词: 蛋黄卵磷脂;结构特性;提取鉴定;功效活性;应用

Abstract: Egg yolk lecithin is a natural animal-derived phospholipid complex, primarily composed of phosphatidylcholine, phosphatidylethanolamine, sphingomyelin, lysophosphatidylcholine, and lysophosphatidylethanolamine, and has multiple bioactivities such as neuroprotection, hepatoprotection, anti-aging, and immunomodulation. Techniques such as solvent extraction, supercritical fluid extraction, membrane separation and column chromatography can effectively isolate lecithin from egg yolk, and the lecithin can be precisely characterized by mass spectrometry (MS)-based lipidomics. Egg yolk lecithin, a unique amphiphilic substance containing a hydrophilic polar phosphate head and a hydrophobic tail consisting of fatty acid chains, can form bilayer vesicles, making it suitable for encapsulating sensitive active substances or small molecule drugs to improve their bioavailability. The application scope of egg yolk lecithin has expanded from traditional foods to high-value-added pharmaceuticals, health foods and cosmetics, showing significant development potential. This article systematically reviews the structural characteristics, extraction and identification methods, bioactivities, and applications of egg yolk lecithin, with a view to providing a theoretical reference for its future research and high-value-added application.

Key words: egg yolk lecithin; structural characterization; extraction and identification; bioactivities; applications

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