食品科学 ›› 2026, Vol. 47 ›› Issue (3): 139-147.doi: 10.7506/spkx1002-6630-20250901-003

• 营养卫生 • 上一篇    下一篇

茶多酚基纳米复合物的构建及其对生殖细胞抗氧化作用

陈梅,隆佳辛,贺圆梦,洪工画,郭俊凌   

  1. (1.四川大学轻工科学与工程学院,四川 成都 610065;2.四川大学 皮革化学与工程教育部重点实验室,制革清洁技术国家工程实验室,四川 成都 610065)
  • 出版日期:2026-02-01 发布日期:2026-03-16
  • 基金资助:
    “十四五”国家重点研发计划重点专项(2022YFA0912800);国家海外高层次人才计划项目(00308054A1045); 国家自然科学基金面上项目(22178233);国家自然科学基金青年科学基金项目(22408241); 中央高校基本科研业务费专项(SCU2025D014)

Construction of Tea Polyphenol-Based Nanocomplex and Its Antioxidant Effects on Reproductive Cells

CHEN Mei, LONG Jiaxin, HE Yuanmeng, HONG Gonghua, GUO Junling   

  1. (1. College of Biomass Science and Engineering, Sichuan University, Chengdu 610065, China; 2. Key Laboratory of Leather Chemistry and Engineering of Ministry of Education, National Engineering Laboratory for Clean Technology of Leather Manufacture, Sichuan University, Chengdu 610065, China)
  • Online:2026-02-01 Published:2026-03-16

摘要: 利用表没食子儿茶素没食子酸酯((-)-epigallocatechin-3-gallate,EGCG)与Zn2+配位形成粒径为50~120 nm的EGCG-ZnII金属-多酚网络纳米复合物,与单独EGCG相比,该金属-多酚纳米复合物不仅显著增强抗氧化性能,并在不同温度和pH值范围内表现出优异的稳定性,同时该金属-多酚纳米复合物可显著降低卵母细胞和子宫内膜上皮细胞氧化应激水平。本研究不仅通过食品多酚构建了新型食品纳米技术平台,还展现了天然食品活性成分向功能型、精准化应用的发展方向。

关键词: 植物多酚;表没食子儿茶素没食子酸酯-ZnII纳米复合物;抗氧化性能;生殖细胞

Abstract: In this study, (–)-epigallocatechin-3-gallate (EGCG) was complexed with Zn2+ ions to form EGCG-ZnII network nanocomplexes with a particle size of 50–120 nm. Compared with EGCG, the metal-phenolic network nanocomplexes exhibited significantly enhanced antioxidant capacity and maintained strong antioxidant activity across a range of temperatures and pH values. Furthermore, the nanocomplexes significantly reduced oxidative stress in both oocytes and endometrial epithelial cells. This research not only develops a food nanotechnology platform based on polyphenols but also highlights the trend toward functional and precision-oriented applications of natural bioactive food components.

Key words: natural polyphenol; (–)-epigallocatechin-3-gallate-ZnII nanocomplexes; antioxidant activity; reproductive cells

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