食品科学 ›› 2003, Vol. 24 ›› Issue (8): 140-141.

• 营养卫生 • 上一篇    下一篇

甘草纤素对实验动物化学性肝损伤保护功能研究

 许秀举, 李美仙, 吴玲   

  1. 包头医学院营养教研室
  • 出版日期:2003-08-15 发布日期:2011-12-13

Study on the Effect of Licorice Root Cellulose on Protecting Against Chemical Hepatic Injury

 XU  Xiu-Ju, LI  Mei-Xian, WU  Ling   

  • Online:2003-08-15 Published:2011-12-13

摘要: 目的:了解甘草纤素对大鼠化学性肝损伤的保护作用。方法:按照卫生部《保健食品功能学评价程序和检验方法》进行。并比较四氯化碳染毒后第48h和第5d处死动物对各项指标的影响。结果:与肝损伤模型对照组比较,染毒后第48h,甘草纤素的二个剂量组血清ALT(丙氨酸氨基转移酶)水平均有显著降低(p<0.05),中、高剂量组血清AST(天门冬氨酸氨基转移酶)水平也有显著降低(p<0.05)。受试物的高剂量组可改善肝细胞的退行性变,且高剂量组可明显减轻CCl4引起的肝细胞坏死(p<0.05)。结论:适量甘草纤素对CCl4所致动物急性肝损伤具有保护作用。

关键词: 甘草纤素, 肝损伤

Abstract: Objective: Through investigiting the protective effect of licorice root sheet on acute chemical hepatic injury inratmodels.Methods: According to the health food functional assessment procedures and testmethods. We compared the alcerationsin the markers of the 48th hour and the 5th day after the jast administration of carbon Cetrachloride(CCl4).Results: When the48th hour after the lass administration of CCl4, there Was significant decrease in blood serum . Alanine aminoransfense(ALT)and Aspartate aminotransferase(AST) of licorice root sheet exposure groups compared with hepatic injure model contral group(p<0.05).Conclusions: Adequate licorice root sheet hod prevension effect from acute CCl4 hepatic injure.

Key words: licorice root sheet, hepatil injure