关键词: 负重游泳, 数学模型, 优化, 抗疲劳, 量效关系

Abstract:  Loaded-swimming time of mouse was main experiment objective. The research of optimizing the best dosage and time of anti-fatigue and anti-hypoxia showed: Compared with conventional method,according to the combination method of orthogonal polynomial mathematics model and genetic algorithms,the best dosage and time of notable anti-fatigue effect was optimized. It could optimize accurately,get the best dosage and time of notable effect,and make the research results more accurate and credible and the judge argument more ample. It has higher accuracy,which impacted by systematic error caused by individual differences of mouse and experiment technology. It is a new feasible method.

Key words:  , loaded-swimming； combination method； optimization； anti-fatigue； best dosage and time；