食品科学

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NADPH代谢对氨基酸生物合成影响的研究进展

陈进聪,陈雪岚,张 斌,熊勇华   

  1. 1.南昌大学中德联合研究院,江西 南昌 330047;2.江西师范大学生命科学学院,江西 南昌 330022
  • 出版日期:2014-10-15 发布日期:2014-10-17

Progress in the Study of NADPH Metabolism in Biosynthesis of Amino Acids

CHEN Jin-cong, CHEN Xue-lan, ZHANG Bin, XIONG Yong-hua   

  1. 1. Sino-German Joint Research Institute, Nanchang University, Nanchang 330047, China;
    2. College of Life Science, Jiangxi Normal University, Nanchang 330022, China
  • Online:2014-10-15 Published:2014-10-17

摘要:

烟酰胺腺嘌呤二核苷酸磷酸(nicotinamide adenine dinucleotide phosphate,NADPH)是微生物代谢重要的辅助因子,其在微生物体内的含量是限制氨基酸合成代谢的一个重要因素。本文从NADPH的生物代谢,NADPH与微生物发酵产氨基酸的关系,以及NADPH的代谢调控策略促进氨基酸的生物合成等,进行简要概述,为进一步提高氨基酸产量提供参考。

关键词: NADPH, 生物代谢, 氨基酸, 发酵, 策略

Abstract:

NADPH is an important cofactor of microbial metabolism, which is a limiting factor in microbial amino acid
anabolism. This article reviews the biosynthesis of NADPH, its relationship with microbial production of amino acids, and
strategies to promote amino aicd biosynthesis by regulating NADPH metabolism with the aim of providing a reference for
improving the yield of amino acids.

Key words: NADPH, metabolism, amino acids, fermentation, strategies

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