食品科学
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黄巧娟,孙志高*,龙 勇,孙 谦
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HUANG Qiaojuan, SUN Zhigao*, LONG Yong, SUN Qian
Online:
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摘要:
D-柠檬烯是一种天然的单萜烯,广泛存在于柑橘、蔬菜及香料中,具有消炎、抑菌、抗肿瘤等多种功效。其中抗癌是D-柠檬烯的主要药理活性之一,其抗癌机制主要包括化学预防作用、抑制细胞周期与诱导细胞凋亡以及抑制肿瘤转移与侵袭等。由于D-柠檬烯具有来源广泛、安全性好、给药方便等优点,具有良好的开发前景和临床应用价值,亟待深入研究。
关键词: D-柠檬烯, 癌症, 抗癌机制, 细胞凋亡
Abstract:
D-Limonene, widely present in citrus, vegetables and spices, is a natural monoterpene. It plays an important role in many physiological processes, such as reducing inflammation, minimizing bacterial growth, and inhibiting cancer development. Anticancer effect is the major function of D-limonene by participating in chemical prevention, cell-cycle inhibition, induction of apoptosis, and defense against cancer proliferation and invasiveness. D-Limonene has great prospects for clinical application for its wide distribution, excellent safety, and convenient administration. Therefore, it is worthy of further exploration.
Key words: D-limonene, cancer, anticancer mechanism, apoptosis
中图分类号:
TS255.1
黄巧娟,孙志高*,龙 勇,孙 谦. D-柠檬烯抗癌机制的研究进展[J]. 食品科学, doi: 10.7506/spkx1002-6630-201507044.
HUANG Qiaojuan, SUN Zhigao*, LONG Yong, SUN Qian. Recent Progress in Research on Anticancer Mechanism of D-Limonene[J]. FOOD SCIENCE, doi: 10.7506/spkx1002-6630-201507044.
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链接本文: https://www.spkx.net.cn/CN/10.7506/spkx1002-6630-201507044
https://www.spkx.net.cn/CN/Y2015/V36/I7/240