食品科学 ›› 2021, Vol. 42 ›› Issue (11): 324-331.doi: 10.7506/spkx1002-6630-20200507-063

• 专题论述 • 上一篇    下一篇

美拉德反应及其产物在递送生物活性物质方面的应用研究进展

王植,刘昊天,刘骞,陈倩,孔保华   

  1. (东北农业大学食品学院,黑龙江 哈尔滨 150030)
  • 出版日期:2021-06-15 发布日期:2021-06-29
  • 基金资助:
    黑龙江省“百千万”工程重大科技专项(2019ZX07B03)

A Literature Review of the Application of Maillard Reaction and Its Products in the Delivery of Bioactive Substances

WANG Zhi, LIU Haotian, LIU Qian, CHEN Qian, KONG Baohua   

  1. (School of Food Science, Northeast Agricultural University, Harbin 150030, China)
  • Online:2021-06-15 Published:2021-06-29

摘要: 生物活性物质作为许多食品和药品中的功能性成分,具有广泛的应用前景。但是生物活性物质在加工、贮存和胃肠道环境中极容易分解,这大大限制了它们的应用。因此,如何设计食品级的递送体系成为研究的热点问题。美拉德反应无需添加化学试剂即可自然发生,已被广泛应用于改善蛋白质的功能特性,蛋白质和多糖经美拉德反应得到的复合物具有良好的稳定性,是近年来应用最广泛的载体之一。本文综述了美拉德反应对蛋白质功能特性的影响,以及近年来蛋白质-多糖共价复合物在乳状液、纳米粒子、纳米凝胶和微胶囊等生物活性物质递送体系中的应用,讨论了递送体系在消化系统中的变化,并展望了美拉德反应在制备递送体系方面的应用前景和需要解决的问题。

关键词: 美拉德反应;蛋白质-多糖共价复合物;生物活性物质;递送体系

Abstract: Bioactive compounds have potential applications as functional ingredients in many foods and medicines. During processing, storage, and gastrointestinal digestion, bioactive substances are easily degraded, which greatly limits their applications. Therefore, researchers have expressed considerable interest in designing a food-grade delivery system. The Maillard reaction occurs naturally without the addition of chemical reagents and has been widely used to improve the functional properties of proteins. The protein-polysaccharide conjugate prepared by the Maillard reaction has high stability, and it has been widely used to deliver bioactive substances in recent years. This article reviews the effect of the Maillard reaction on the functional properties of proteins, and the applications of the protein-polysaccharide conjugate in delivery systems for bioactive substances such as emulsions, nanoparticles, nanogels, and microcapsules. Also, how the delivery systems change during digestion is discussed. Moreover, the problems to be solved and future prospects for the application of the Maillard reaction in the preparation of delivery systems are discussed.

Key words: Maillard reaction; protein-polysaccharide conjugate; bioactive compound; delivery system

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