食品科学 ›› 2023, Vol. 44 ›› Issue (7): 18-28.doi: 10.7506/spkx1002-6630-20221003-107

• 海洋功能食品专栏 • 上一篇    下一篇

海洋生物活性肽生物学和功能特性的研究进展

闫洪波,楚英珂,李雯慧,张德景,杨青,位正鹏,王宗敏,王彦波,朱兰兰   

  1. (1.山东理工大学农业工程与食品科学学院,山东 淄博 255000;2.荣成泰祥食品股份有限公司,山东 荣成 264300)
  • 出版日期:2023-04-15 发布日期:2023-04-25
  • 基金资助:
    山东省重大科技创新工程项目(2022CXGC020414);山东省重大科技创新示范项目(2021SFGC0701)

Advances in Research on Biological and Functional Properties of Bioactive Peptides Derived from Marine Sources

YAN Hongbo, CHU Yingke, LI Wenhui, ZHANG Dejing, YANG Qing, WEI Zhengpeng, WANG Zongmin, WANG Yanbo, ZHU Lanlan   

  1. (1. College of Agricultural Engineering and Food Science, Shandong University of Technology, Zibo 255000, China; 2. Rongcheng Taixiang Food Products Co., Ltd., Rongcheng 264300, China)
  • Online:2023-04-15 Published:2023-04-25

摘要: 海洋生物活性肽具有抗氧化、抗高血压和抗动脉粥样硬化等生物学特性。海洋来源的抗氧化肽分子质量一般低于3 kDa,多数为胃蛋白酶水解产生。海洋来源的抗高血压肽分子质量一般低于1.5 kDa,具有血管紧张素转化酶抑制活性。小球藻中提取的多肽可抑制内皮细胞选择素的产生,具有抗动脉粥样硬化活性。唇贻贝中性蛋白酶水解多肽可促进血小板内皮细胞黏附分子-1、成纤维细胞生长因子和表皮生长因子增殖,具有皮肤伤口修复功能。在鱼类副产物及其水解蛋白中提取的多肽,水解度越高溶解性越高,起泡和乳化性能良好。本文旨在综述从不同海洋来源分离的生物活性肽的信息,重点介绍其不同的生物活性和功能特性,以及不同的工业应用,以期推动海洋生物活性肽功能产品开发,并为其生物学和功能特性的深入研究提供理论参考。

关键词: 生物活性肽, 生物学特性, 功能特性, 工业应用

Abstract: Bioactive peptides from marine sources have a broad spectrum of biological properties, including antioxidant, anti-hypertensive and anti-atherogenic activity. The molecular mass of antioxidant peptides from marine sources is generally less than 3 kDa, and most of them are produced by pepsin hydrolysis. The molecular mass of antihypertensive peptides from marine sources, which have angiotensin converting enzyme inhibitory activity, is generally less than 1.5 kDa. Peptides extracted from chlorella can inhibit the production of endothelial cell selectin and have anti-atherosclerotic activity. Peptides derived from the hydrolysis of green-lipped mussel by neutral protease can promote the proliferation of platelet endothelial cell adhesion molecule 1, fibroblast growth factor and epidermal growth factor, and repair skin wound. Peptides derived from proteins in fish processing byproducts have good foaming and emulsifying properties; the higher the degree of hydrolysis, the better the solubility. This article aims to review the information on bioactive peptides isolated from different marine sources, with focus on different biological activities and functional properties as well as different industrial applications. It is expected to promote the development of functional products from bioactive peptides derived from marine sources and provide a theoretical reference for further studies on their biological and functional characteristics.

Key words: bioactive peptides, biological properties, functional properties, industrial applications

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