食品科学 ›› 2023, Vol. 44 ›› Issue (11): 356-366.doi: 10.7506/spkx1002-6630-20220507-092

• 专题论述 • 上一篇    

化学与生物法制备乳糖酯及其在食品应用中的研究进展

金锐,石玉刚,孔一鸣,吕梦蝶,章一凡,石泽宇,Rammile ETTELAIE   

  1. (1.浙江工商大学食品与生物工程学院,浙江 杭州 310035;2.浙江工商大学食品微生物研究所,浙江 杭州 310035;3.浙江树人学院生物与环境工程学院,浙江 杭州 310015;4.利兹大学食品科学与营养学院,英国 利兹 LS29JT)
  • 发布日期:2023-06-30
  • 基金资助:
    浙江省基础公益研究项目(LGJ19C200001);浙江省教育厅科研项目(Y201016439); 浙江省引智项目(Z20170407);一流学科建设国际合作研究项目(2017SICR109)

Chemical versus Biological Synthesis of Lactose Esters and Their Application in Food Industry

JIN Rui, SHI Yugang, KONG Yiming, LÜ Mengdie, ZHANG Yifan, SHI Zeyu, Rammile ETTELAIE   

  1. (1. School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310035, China; 2. Institute of Food Microbiology, Zhejiang Gongshang University, Hangzhou 310035, China; 3. College of Biology and Environmental Engineering, Zhejiang Shuren University, Hangzhou 310015, China; 4. School of Food Science and Nutrition, University of Leeds, Leeds LS29JT, UK)
  • Published:2023-06-30

摘要: 糖酯是一类非离子型生物表面活性剂,相较于传统表面活性剂,其具有良好的乳化性、抗菌能力及生物可降解性,被广泛应用于食品、化妆品和医药等领域。相较于目前研究最广的蔗糖酯,乳糖酯(lactose esters,LEs)表现出更为优异的物化与生物学性质,具有广阔应用前景。本文综述近年来化学与生物法制备LEs的研究进展,以及LEs作为食品添加剂在产品乳化和抑菌防腐等方面的应用情况;并总结其在微生物动力学失活和光动力治疗等领域的研究和应用潜力,同时指出LEs制备与拓展应用中存在的问题与发展前景,以期为LEs的深度开发和研究提供借鉴。

关键词: 乳糖酯;化学合成;酶催化;抑菌活性;乳化;光动力杀菌;抗癌

Abstract: Sugar esters are non-ionic biosurfactants. In comparison to traditional surfactants, sugar ester biosurfactants have superior emulsifying, antibacterial, and biodegradable properties, and are widely utilized in foods, cosmetics, medicine, and other sectors. Compared to sucrose esters, the most investigated sugar esters, lactose esters (LEs) exhibit superior physicochemical and biological properties and have more promising applications. This article focuses on recent advances in the manufacture of LEs using chemical and biological methods, as well as their application as emulsifiers and antibacterial materials. The application potential of LEs in the fields of bacterial photodynamic inactivation and photodynamic therapy is summarized. In addition, some problems with the preparation and application of LEs as well as their future prospects are discussed in order to provide a reference for intensive research and development of LEs.

Key words: lactose esters; chemical synthesis; enzymatic catalysis; antimicrobial activity; emulsification; bacterial photodynamic inactivation; anticancer

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