FOOD SCIENCE ›› 2009, Vol. 30 ›› Issue (18 ): 176-180.doi: 10.7506/spkx1002-6300-200918037

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Extraction of Cordycepin from Fermented Mycelia of Cordyceps militaris: A Comparitive Study of Ultrasonic-assisted and Microwave-assisted Procedures

HUANG Zi-qi1,BEN Song-bin1,SANG Yu-li2,DAI Ying2,LI Hui-jiao2,CHEN Chang-lan2,*   

  1. 1. School of Life Science, Liaoning University, Shenyang 110036, China;
    2. School of Pharceutical Science, Liaoning University, Shenyang 110036, China
  • Received:2009-06-22 Online:2009-09-15 Published:2010-12-29
  • Contact: CHEN Chang-lan E-mail:chenchanglanbio@yahoo.com.cn

Abstract:

Ultrasonic and microwave techniques were separately used to assist the extraction of cordycepin from fermented mycelia of Cordyceps militaris with ethanol. On the basis of single factor experiments, ultrasonic-assisted and microwave-assisted extraction procedures were optimized for maximizing yield of cordycepin using L9(34) orthogonal array design. The results showed that the assisting effect of microwave was better than that of ultrasonic, and a maximum yield of cordycepin was obtained under the following extraction conditions: microwave power, 500 W; extraction solvent, a mixture of water and absolute ethanol (1:3, V/V) at pH 7.0; and extraction time 3 min.

Key words: cordycepin, extraction, microwave, ultrasonic, orthogonal design

CLC Number: