Effect of Luteolin on Blood Lipid Level and Antioxidant Capability in Hyperlipidemic Rats

doi:10.7506/spkx1002-6300-200921081

FOOD SCIENCE ›› 2009, Vol. 30 ›› Issue (21): 348-350.doi: 10.7506/spkx1002-6300-200921081

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Effect of Luteolin on Blood Lipid Level and Antioxidant Capability in Hyperlipidemic Rats

REN Peng，HE Xin-sheng，LIU Chao

College of Life Science and Engineering, Southwest University of Science and Technology,Mianyang 621010, China

Received:2008-11-17 Revised:2009-06-26 Online:2009-11-01 Published:2010-12-29
Contact: REN Peng E-mail:renpeng@swust.edu.cn

Abstract

Abstract:

High, medium and low doses of luteolin were administered to high fat diet-induced hyperlipidemic rat model established in adult Sprague-Dawley rats for investigating its effects on the levels of blood lipid and antioxidant indexes in hyperlipidemia rats, including MDA content, T-AOC, and SOD and CAT activities. Results showed that all three dose groups exhibited significantly lower levels of TC, TG and MDA and higher levels of HDL-C, T-AOC, SOD and CAT when compared with model control group (P < 0.05). In conclusion, luteolin might contribute to improve the serum antioxidant capability and reduce the lipid peroxidative damage in hyperlipidemic rats.

Key words: luteolin, hyperlipidemia, antioxidant capability

CLC Number:

TQ464.3

REN Peng，HE Xin-sheng，LIU Chao. Effect of Luteolin on Blood Lipid Level and Antioxidant Capability in Hyperlipidemic Rats[J]. FOOD SCIENCE, 2009, 30(21): 348-350.

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Effect of Luteolin on Blood Lipid Level and Antioxidant Capability in Hyperlipidemic Rats

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