Immune Regulation Function of Selenium-enriched Barley Seedling in Mice

doi:10.7506/spkx1002-6300-200923090

FOOD SCIENCE ›› 2009, Vol. 30 ›› Issue (23 ): 401-405.doi: 10.7506/spkx1002-6300-200923090

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Immune Regulation Function of Selenium-enriched Barley Seedling in Mice

XIAO Yan-yan1，WANG Xiao-jie1,*，DAI Xiao-man1，LIU Xin-sheng2，QU Yan-qing2，DU Rong1，LI Qin-yu1，ZHANG Long1

1. College of Life Science, Ludong University, Yantai 264025, China；
2. College Hospital, Ludong University, Yantai 264025, China

Received:2009-08-13 Online:2009-12-01 Published:2010-12-29
Contact: WANG Xiao-jie E-mail:wxj10304@126.com

Abstract

Abstract:

Objective: To observe immune regulation function of selenium-enriched barley seedling (SEBS) in mice by detecting cell-mediated immunity and humoral immunity. Methods: Experimental mice were orally administered with SEBS at doses of 1, 0.5 g/ml and 0.1 g/ml. Meanwhile, two groups were also orally administered with saline water at the same volume and regular barley seedling at the dose of 1 g/ml as the controls. Total number of white blood cell (WBC), phagocytosis test of macrophage on abdominal cavity, titer of antibody, number of antibody-producing cells and weight of immune organs in mice were determined. Results: Compared to saline water group, SEBS could significantly improve phagocytic function of macrophages (P＜0.01), obviously increase the titer of anti-CRBC antibody (P＜0.05), spleen index (P＜0.05), and total number of WBC (P＜0.05). Conclusion: SEBS can promote cell-mediated immunity and humoral immunity in mice in a dosedependent manner.

Key words: selenium-enriched barley seedling, immune function, mice

CLC Number:

TS210.1

XIAO Yan-yan1，WANG Xiao-jie1,*，DAI Xiao-man1，LIU Xin-sheng2，QU Yan-qing2，DU Rong1，LI Qin-yu1，ZHANG Long1. Immune Regulation Function of Selenium-enriched Barley Seedling in Mice[J]. FOOD SCIENCE, 2009, 30(23 ): 401-405.

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Immune Regulation Function of Selenium-enriched Barley Seedling in Mice

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