FOOD SCIENCE ›› 2009, Vol. 30 ›› Issue (3): 21-24.doi: 10.7506/spkx1002-6630-200903002

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Kinetics on Extraction of Triterpenoids from Antrodia camphorata

LU Zhen-ming1, TAO Wen-yi1,*,XU Hong-yu2,AO Zong-hua1,ZHANG Xihao-mei2,XU Zheng-hong1,2   

  1. (1.Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China ;
    2. Laboratory of Pharmaceutical Engineering, School of Medicine and Pharmaceutics, Jiangnan University, Wuxi 214122, China)
  • Received:2008-03-06 Revised:2008-08-04 Online:2009-02-01 Published:2010-12-29
  • Contact: LU Zhen-ming1 E-mail:zhenming_lu@yahoo.com.cn

Abstract:

The Fick's second law of diffusion was used to establish the kinetics equation of extracting triterpenoid parameters from Antrodia camphorata in submerged fermentation. The extraction process was analyzed to obtain kinetics parameters, such as K (rate constant), Ea (activation energy), y (yield), t1/2 (half life)and Ds (internal diffusion coefficient). The results showed that the kinetics on the extraction of triterpenoids match the first-order rate equation, and the rate-determining step for extraction is the diffusion of triterpenoids through particles. The method would be useful for the process design and the choice of operation condition to extract triterpenoids from Antrodia camphorata in subm erged fermentation.

Key words: Antrodia camphorata, submerged culture, triterpenoid, extraction, kinetics

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