Abstract:

Neotame is a new type, high efficiency, non-nutrition sweetener. In this study, neotame was synthesized directly from aspartame. In the presence of hydrogenation catalyst Pd/C, aspartame and 3,3-dimethyl butyraldehyde were reacted in methanol solution. Then after crystallization and drying, white crystal neotame was obtained. This experiment was performed under mild conditions and high purity product with yield of 61% was obtained.

Key words: neotame, aspartame, 3,3-dimethyl butyraldehyde