Blood Glucose-reducing Effects of Fructus phyllanthi Fruit Extracts on Diabetic Mice

doi:10.7506/spkx1002-6630-200909051

FOOD SCIENCE ›› 2009, Vol. 30 ›› Issue (9): 210-212.doi: 10.7506/spkx1002-6630-200909051

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Blood Glucose-reducing Effects of Fructus phyllanthi Fruit Extracts on Diabetic Mice

HAN Gang YUAN Hai-zhong DONG Yue ZHAI Guan-yu FAN Ying

Tangshan Key Laboratory of New Drug Research, Pharmaceutical Department, North China Coal Medical
University, Tangshan 063000, China

Received:2008-08-25 Revised:2008-12-29 Online:2009-05-01 Published:2010-12-29
Contact: HAN Gang E-mail:tsyxhg@163.com

Abstract

Abstract:

In this study, diabetic mice model was established by intravenous injection of 70 mg/kg alloxan. Then the mice were administered with metformin (the positive control), and ethanol extract and aqueous extract of Fructus pyhlllanthi fruit by gastric perfusion, respectively, to investigate the effects of ethanol and aqueous extracts on blood glucose level of diabetic mice. The results showed that the aqueous extract can significantly decrease the blood glucose level in diabetic mice (p＜0.05), but there is only a hypoglycemic tendency induced by ethanol extract without statistical significance (p＞0.05).

Key words: Fructus phyllanthi, diabetes mellitus, blood glucose, alloxan

CLC Number:

R284.2

HAN Gang YUAN Hai-zhong DONG Yue ZHAI Guan-yu FAN Ying. Blood Glucose-reducing Effects of Fructus phyllanthi Fruit Extracts on Diabetic Mice[J]. FOOD SCIENCE, 2009, 30(9): 210-212 https://doi.org/10.7506/spkx1002-6630-200909051

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Blood Glucose-reducing Effects of Fructus phyllanthi Fruit Extracts on Diabetic Mice

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