Abstract:

Mice subjected to experiments were randomly divided into four groups of 72 each (control group, low-, middle- and high-dose groups), which were fed silkworm pupa protein polypeptide at doses of 0, 0.6, 1.2 and 2.4g/kg·d for 28 days, respectively. Pole-climbing time and weigh-loaded swimming time of mice were recorded. Along with this, serum urea nitrogen, liver glycogen, muscle glycogen and serum lactate of mice before swimming and after swimming at time points of 0, 15 and 60 min were determined. Results indicate that silkworm polypeptides could significantly prolong pole-climbing time and maximum weight-loaded swimming time, promote synthesis of liver glycogen and muscle glycogen, decrease serum urea nitrogen and lactate. Therefore, silkworm pupa protein polypeptides have significant anti-fatigue function.

Key words: silkworm pupa protein, polypeptides, anti-fatigue