FOOD SCIENCE ›› 2009, Vol. 30 ›› Issue (24): 126-129.doi: 10.7506/spkx1002-6630-200924025

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Extraction and Anti-microbial Activity of Chelerythrine from Chelidonium majus

FAN Hai-yan1,XUE Guang-hou1,LU Chun-mao2,CUI Na1   

  1. 1. College of Biological Science and Technology, Shenyang Agricultural University, Shenyang 110161, China;
    2. College of Food Science, Shenyang Agricultural University, Shenyang 110161, China
  • Received:2009-07-13 Revised:2009-09-16 Online:2009-12-15 Published:2010-12-29
  • Contact: LU Chun-mao2, E-mail:lvchunmao@126.com

Abstract:

The extraction technology of chelerythrine from Chelidonium majus L. was studied. The main factors influencing the chelerythrine extraction and their best levels were aanlyzed by the single factor analysis, and the extraction conditions were optimized by the orthogonal test. The results showed that the optimal condition was obtained with the liquid/solid ratio of 1:20 for 35 min extraction under 700 W of ultrasonic power. The chelerythrine extracts displayed a certain inhibitory effect on Fusarium oxysporum f. sp. melonis, Fusarium oxysporum f. sp. niveum, Verticillium dahliae, Fusarium oxysporum f. sp. cucumerinum, Vermicularia capsici, Glomerella cingulata, Botrytis cinerea, Sclerotinia sclerotiorum.

Key words: Chelidonium majus, chelerythrine, separation, anti-fungal activity

CLC Number: