FOOD SCIENCE ›› 2009, Vol. 30 ›› Issue (24 ): 238-241.doi: 10.7506/spkx1002-6630-200924050

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Degradation Condition of Hyaluronic Acid from Squid Eyes

WANG Jing,YANG Jia-yu,JIN Miao,MA Jin-lian,LU Jia-fang,YANG Wen-ge*   

  1. Key Laboratory of Applied Marine Biotechnology, Ministry of Education, Faculty of Life Science and Biotechnology,
    Ningbo University, Ningbo 315211, China
  • Received:2009-08-15 Online:2009-12-15 Published:2010-12-29
  • Contact: YANG Wen-ge* E-mail:yangwene@nbu.edu.cn

Abstract:

Hyaluronic acid (HA) is a unique acidic mucopolysaccharide with multiple physiological functions so that it is widely applied in the fields of medicine and food due to its various molecular weights. Squid eyes were used as raw materials to study degradation condition of HA through physical and chemical methods. Molecular weight was used as the index to evaluate degradation condition. Results indicated that HA could be effectively degraded by a combinatorial method of hydrogen peroxide and ascorbic acid. The optimal degradation condition was 3:1 of mole ratio between hydrogen peroxide and ascorbic acid, pH 4.0, 15 min of reaction time, 50 ℃ of reaction temperature. The molecular weight of HA could be degraded to 5433 under this optimal condition.

Key words: quid eyes, hyaluronic acid, degradation, molecular weight

CLC Number: