Effect of Cordyceps militaris on Oxidases in Brain and Liver Tissues of D-Galactose-induced Senile Mice

doi:10.7506/spkx1002-6630-201019074

FOOD SCIENCE ›› 2010, Vol. 31 ›› Issue (19): 339-341.doi: 10.7506/spkx1002-6630-201019074

• Nutrition & Hygiene • Previous Articles Next Articles

Effect of Cordyceps militaris on Oxidases in Brain and Liver Tissues of D-Galactose-induced Senile Mice

YANG Zhan-jun，ZHANG Jian，TANG Yang，WEN Lu

School of Life Science, Huaiyin Normal University, Huai’an 223300, China

Received:2009-12-16 Online:2010-10-15 Published:2010-12-29
Contact: YANG Zhan-jun E-mail:yzj5678@163.com

Abstract

Abstract:

Objective: The enzymes related to aging were used as the indexes to explore the effect of Cordyceps militaris on Dgalactose-induced senile mice. Methods: A mouse model with senile disturbance of brain tissue was established by D-galactose induction and the experimental mice were treated with Cordyceps militaris by gavage. After the administration of Cordyceps militaris for six weeks, the activities of T-AOC, GSH-Px, MAO and the content of MDA in brain and liver tissues were analyzed. Results: Compared with the control group, the activities of T-AOC and GSH-Px of the model group exhibited an obvious decrease, and the activity of MAO and the content of MDA exhibited a significant increase (P ＜ 0.05 or P ＜ 0.01). Compared with the model group, the activities of T-AOC and GSH-Px in mice administered with Cordyceps militaris was ameliorated, and the activity of MAO and the content of MDA exhibited an obvious decrease (P ＜ 0.05). Conclusion: Cordyceps militaris can improve the antioxidant capability of brain and liver tissues.

Key words: Cordyceps militaris, D-galactose, senile, oxidase

CLC Number:

TQ929.2

YANG Zhan-jun，ZHANG Jian，TANG Yang，WEN Lu. Effect of Cordyceps militaris on Oxidases in Brain and Liver Tissues of D-Galactose-induced Senile Mice[J]. FOOD SCIENCE, 2010, 31(19): 339-341.

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Effect of Cordyceps militaris on Oxidases in Brain and Liver Tissues of D-Galactose-induced Senile Mice

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