Effect ofα-Linolenic Acid from Silkworm pupa Oil on Experimental hyperlipidemia in Rats

doi:10.7506/spkx1002-6630-201115063

Abstract

Abstract: Objective: To investigate the preventive and therapeutic effects of α-linolenic acid from silkworm pupa oil in hyperlipidemic rats. Methods: Hyperlipidemia in SD rats was induced by feeding high-fat diet. α-Linolenic acid from silkworm pupa oil was also fed to the model rats. The contents of serum triglyceride (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and apolipoprotein AI (Apo A-I) were determined, and the activities of lipoprotein lipase (LPL) and hepatic lipase (HL) were analyzed. Results: α-Linolenic acid from silkworm pupa oil could result in a significant decrease in the contents of TC and TG, and an increase in the contents of HDL-C and Apo A-I and the activities of LPL and HL in hyperlipidemia rat serum. Conclusion: α-Linolenic acid from silkworm pupa oil has significantly preventive and therapeutic effects in hyperlipidemia rats.

Key words: silkworm pupa oil, α-linolenic acid, blood lipids, apolipoprotein, lipoprotein lipase

CLC Number:

TS201.4

WU Xiao-xia，LI Jian-ke，LIU Ying-li. Effect ofα-Linolenic Acid from Silkworm pupa Oil on Experimental hyperlipidemia in Rats[J]. FOOD SCIENCE, 2011, 32(15): 285-288.

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Effect ofα-Linolenic Acid from Silkworm pupa Oil on Experimental hyperlipidemia in Rats

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