FOOD SCIENCE ›› 2011, Vol. 32 ›› Issue (1 ): 203-205.doi: 10.7506/spkx1002-6630-201101048

• Nutrition & Hygiene • Previous Articles     Next Articles

An Experimental Animal Investigation on Toxicity and Blood Lipid Modulating Effect of Kadsura coccinea Fruit

LI Zhi-chun1,2，SUN Jian1,2,*，FENG Yi3，ZHUO Shao-yuan3，LE Ning3，YAO Jin-yan4，LONG Xing4   

  1. 1. Institute of Agro-food Science & Technology, Guangxi Academy of Agricultural Sciences, Nanning 530007 China；2. Guangxi Crop Genetic Improvement Laboratory, Nanning 530007, China； 3. Faculty of Preclinical Medicine, Guangxi Traditional Chinese Medical University, Nanning 530001 China；4. Horticultural Research Institute, Guangxi Academy of Agricultural Sciences, Nanning 530007, China
  • Received:2010-04-16 Online:2011-01-15 Published:2010-12-28
  • Contact: SUN Jian E-mail:jiansun@yahoo.cn

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Abstract:

The aim of this study was to investigate the toxicity and blood lipid modulating effect of ripe Kadsura conccinea fruit in vivo by maximal tolerance dose (MTD) test and 30-d feeding test in mice. Blood lipid changes in mice were analyzed during 30 days of Kadsura conccinea fruit feeding. The results showed MTD was ＞ 20 mL/kg for both male and female mice, indicating that Kadsura conccinea fruit was non-toxic. Kadsura conccinea fruit had significant effect on neither mouse weight nor viscera but could obviously reduce the level of cholesterol in mouse blood. Thus, it can be considered that ripe Kadsura conccinea fruit deserves to be exploited as a rare wild fruit with the benefits of non-toxicity and modulating blood lipids.

Key words: Kadsura conccinea fruit, toxicity, blood lipids, modulating

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