Abstract: Colloidal gold immunochromatographic assay (GICA) and gas chromatography (GC) was separately used for the analysis of chloramphenicol (CAP) residues in creatural products. Samples were spiked with 0.3, 0.5μg/kg and 1.5μg/kg CAP and determined by the methods. CAP residues at concentrations above 0.5μg/kg could be detected by GICA. The average recovery rates of GC were 78.1%, 85.3% and 88.3%, respectively with relative standard deviation (RSD) of 5.3%－9.0% and the detection limit was 0.3μg/kg. Three positive samples and other 105 samples analyzed by GICA were confirmed by GC and no false positive and negative samples were observed. Therefore, GICA is a rapid, accurate, reproducible and suitable to be used for rapid in situ screening of CAP residues in food products of animal origin, while GC is sensitive and suitable to be used for quantification of positive samples.

Key words: food products of animal origin, chloramphenicol, GICA, GC