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Biosynthetic Pathways of B-Group Vitamins in Lactococcus lactis subsp. lactis KLDS4.0325

YANG Xiao-chun, WANG Yu-tang, HUO Gui-cheng   

  1. Key Laboratory of Dairy Science, Ministry of Education, Northeast Agricultural University, Harbin 150030, China
  • Online:2014-04-15 Published:2014-04-18

Abstract:

In order to exploit the potential of Lactococcus lactis subsp. lactis KLDS4.0325 for synthesizing B-groupvitamins, the sequences of proteins involved in the biosynthetic pathways of all kinds of B-group vitamins were used toperform a BLASTp search against the amino acid sequence of L. lactis KLDS4.0325, and comparative analysis with other 9L. lactis strains. Results showed that compared with the reference strains, L. lactis KLDS4.0325 possessed relativelycomplete genes encoding proteins involved in the biosynthetic pathways of folate and riboflavin, could efficiently synthesizefolate and riboflavin at the genetic level. Thus this strain will have a number of potential applications.

Key words: L. lactis KLDS4.0325, folate, riboflavin, B-group vitamin, biosynthetic pathways