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A Review on the Structure and Immune Regulation Function of Lactobacillus S-Layer Protein

ZHANG Yingchun1,2, XIANG Xinling1, ZHANG Lanwei1, MA Fang2, LI Shaohui1   

  1. 1. School of Chemical Engineering and Technology, Harbin Institute of Technology, Harbin 150090, China;
    2. School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China
  • Online:2016-02-15 Published:2016-02-26

Abstract:

The structure and function of Lactobacillus S-layer protein are reviewed in this paper with special focus on its
tolerance to digestive enzymes and bile salts, involvement in host cell adhesion of Lactobacillus and role in inhibiting host
cell adhesion and intrusion by pathogens. Meanwhile, the regulatory effect of Lactobacillus S-layer protein on cell signaling
pathways is expounded. In conclusion, this review suggests that Lactobacillus S-layer protein plays an important role in the
immunoregulatory effect of Lactobacillus.

Key words: Lactobacillus, S-layer protein, signaling pathways, immunoregulation

CLC Number: