FOOD SCIENCE

• Processing Technology • Previous Articles     Next Articles

Optimization of Purification Process for Dihydroquercetin in Larch Roots by Response Surface Methodology

WANG Jiaqi, SONG Mingming, CHEN Kai, WANG Yueliang, DING Chuanbo, ZHENG Yinan, SHEN Lei, LIU Wencong   

  1. College of Traditional Chinese Medicine, Jilin Agricultural University, Changchun 130118, China
  • Online:2016-02-25 Published:2016-02-23
  • Contact: LIU Wencong

Abstract:

Objective: To optimize the purification conditions for dihydroquercetin in larch roots. Methods: Single factor
method combined with Box-behnkn response surface methodology was used to optimize four factors including solid/liquid
ratio, recrystallization temperature and time by establishing a model involving four independent variables at three levels each
based on dihydroquercetin purity. Results: The optimal purification conditions were determined as recrystallized for 20 h at
5 ℃ at a liquid-to-solid ratio of 1:12 (dihydroquercetin: water). Conclusion: The results of the study can provide scientific
basis for the determination of the purification process of dihydroquercetin in industrial production.

Key words: dihydroquercetin, recrystallization, response surface methodology

CLC Number: