Geometric Isomer Composition of Lycopene from Rat Liver

doi:10.7506/spkx1002-6630-201613034

Abstract

Abstract:

Total lycopene amount and lycopene geometric isomer composition of rat liver were determined in this study,
aiming to lay a foundation for in vivo studies on lycopene metabolism and biological function. In the experiment, male
rats were administrated with tomato extract at a single dose. After 8 h, liver tissues were collected for the extraction of
lycopene. The total amount and geometric isomer composition of lycopene were determined by C30-high performance liquid
chromatography with photodiode array detection (C30-HPLC-PDA). Results indicated that total amount of lycopene from
liver tissues was 92.95 μg/g fresh weight. In comparison with tomato extract, the composition and amount of lycopene
Z-isomers (including 13Z-, 11Z-, 9Z- and 5Z-isomer) were increased in rat liver tissues. This phenomenon is important for
investigating the storage, targeting transfer and biological function of lycopene in liver.

Key words: lycopene, geometric isomer, liver, metabolism

CLC Number:

TS201.2

HUI Bodi, FENG Runyue, GONG Ping. Geometric Isomer Composition of Lycopene from Rat Liver[J]. FOOD SCIENCE, doi: 10.7506/spkx1002-6630-201613034.

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