FOOD SCIENCE

• Processing Technology •     Next Articles

Optimization of Combinations of Methanobactin, Sodium Benzoate and Potassium Sorbate for Enhanced Antibacterial Effect by Response Surface Methodology

XING Haili, XIN Jiaying*, WANG Yan, GAO Shengbo   

  1. Key Laboratory for Food Science and Engineering, Harbin University of Commerce, Harbin 150076, China
  • Online:2016-09-25 Published:2016-09-26
  • Contact: XIN Jiaying

Abstract:

One-factor-at-a-time method and response surface methodology were applied jointly to study the individual
and combined effects of methanobactin, sodium benzoate and potassium sorbate on inhibition zone diameters against
Staphylococcus albus. As a result, a regression model was developed using inhibition zone diameter as response variable.
The analysis carried out using Design-Expert software showed that the maximum inhibition zone diameter of 34.99 mm was
obtained by the combined use of methanobactin, sodium benzoate and potassium sorbate at a mass ratio of 0.330:0.309:0.144,
representing a minimum inhibitory concentration against S. albus of 0.05 mg/mL.

Key words: methanobactin, chemical preservative, blends, antimicrobial effect, response surface methodology

CLC Number: