Abstract: Objective: To discuss the hypolipidemic, hepatoprotective and laxative effects of dietary fiber from Passiflora edulis fruit peel. Methods: An animal model of hyperlipidemia was established by feeding mice with a high-fat diet in this study, and the mice were gavaged with the dietary fiber modified by the wet method at low, medium and high doses for six weeks. Parameters of interest were measured in the blood and viscera of the mice were measured during the period. Results: The serum levels of total cholesterol (TC), triglyceride (TG), and malondialdehyde (MDA) activity in the positive control group, high dose group, and middle dose group decreased compared with the model group. Moreover, the levels of alanine aminotransferase (ALT), aspertate aminotransferase (AST), high-density lipoprotein (HDL-C), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD) were improved to some extent. The levels of low-density lipoprotein (LDL-C) in the high dose group and middle dose group were significantly reduced in contrast to the model group. Conclusion: The dietary fiber has good capacity to reduce blood fat and protect liver function in a dose-dependent manner. Although not significant different from each other in terms of the stool quantity, the various dose groups presented a significant increase in the fecal moisture content, indicating that the modified fiber to be effective in preventing constipation.

Key words: Passiflora edulis peel, dietary fiber, hypolipidemic, liver protection, laxative