Study on Solubilization of Cholesterol by β-Cyclodextrin in Aqueous Solution

Abstract

Abstract: The solubilization of cholesterol by β-cyclodextrin(β-CD)in apueous solution was investigated in this paper.The results showed that the solubilization coefficient(St/S0)of cholesterol had a maximal value(about 1.8).By means of linear regression,it was demonstrated that β-CD with cholesterol could form stable ratio of 2∶1 inclusion complex in aqueous solution before maximal solubilization.Accoding to the molecular size-match and polarity the possible, configuration of 2∶1 inclusion complex was envisaged.

Key words: Cholesterol , β-Cyclodextrin , Solubilization , Configuration

YONG Guo-Ping, FANG Zhi-Yong, TONG Hong-Wu, LIU Shao-Min. Study on Solubilization of Cholesterol by β-Cyclodextrin in Aqueous Solution[J]. FOOD SCIENCE, 2002, 23(3): 40-42.

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Study on Solubilization of Cholesterol by β-Cyclodextrin in Aqueous Solution

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