Cholesterol-degrading Activity of Lactobacillus casei Isolated from Tibet Koumiss

Abstract

Abstract: Cholesterol-degrading strains KM-16 was isolated from Tibet traditional koumiss.Using VITEK-32 AutomaticMicrobe Analytic Systems,the isolate was identified as lactobacillus casei.In MRS medium,KM-16 strain showed 51.8% ofcholesterol was degraded.The cholesterol-degrading activities of the strains were mainly due to their bile salt coprecipitionactivity and the cholesterol asimilation.The effects of KM-16 on the total serum cholesterol(TC),triglycerids(TG) and high densitycholesterol(HDL-C)were investigated in artificially-induced hyperlipemial mice.The results showed that the mean values for TCand TG concentrations decreased significantly after feeding 14d while HDL-C in serum increased at the same time.

Key words: tibet koumiss, lactobacillus casei, cholesterol degradation, hyperlipidemia

XIAO Lin-Lin, DONG Ming-Sheng. Cholesterol-degrading Activity of Lactobacillus casei Isolated from Tibet Koumiss[J]. FOOD SCIENCE, 2003, 24(10): 142-145.

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Cholesterol-degrading Activity of Lactobacillus casei Isolated from Tibet Koumiss

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