Abstract: In order to decrease experiment times and the amount of tested mice, to decrease error caused by the difference of individual mouse, to decrease the fortuitous factors of functional evaluation, and overcome dissimilarity of the appearance of result, we did some animal experiments. The result of measuring the periphery blood targets of mice shows: different experiment time and stay time caused different results in Erythrocyte(RBC), Hemoglobin(HB), The bulk of condensation of the erythrocyte(HCT), Equally erythrocyte bulk(MCV), Equally the erythrocyte hemoglobin(MCH)、Equally erythrocyte hemoglobin concentration(MCHC).There will be some fruits if the alterable situation of the periphery blood targets of mice, which tested only 30days or 15days, were used in evaluating their anti-hypoxia. Therefore, In order to get accurate and objective evaluating results, the periphery blood targets of mice should be synthetically analyzed by different experiment time and stay time.

Key words: animal experiment, the periphery blood targets of mice, anti-hypoxia, functional evaluation measure, study on