Abstract: Objective To investigate the effect of Black Mulberry Fruit(Morus alba L.) on lipia metabolism in rats fed high- fat diet. Methods Wistar rats were randomly divided into 3 groups and fed on basal diet, high-fat diet (basal diet with 10% lard and 1% cholesterol), test diet (high-fat diet with 10% black mulberry dried fruit) for 4 weeks. Results The results showed for hyperlipidemia rats, the high-fat diet with10% black mulberry dried fruit l can markedly decrease the serum TC、TG、LDL- c、 AI and liver TC、TG, meanwhile can increase serum HDL-c and AAI. Conclusion Black mulberry dried fruit has effects on hypolipidemic and anti-atherosolerosis.

Key words: black mulberry dried Fruit, serum lipid, Liver lipid, atherosclerosis, rat