The Possibility of Using Hyperlipemia Mice as Model for Evaluating the Function of Declining Blood Lipids Food

Abstract

Abstract: Objective: Establish a hyperlipemia mice model instead of rat model and investigate the possibility for detecting blood lipids functional food. MethodMice feed on high lipids food. Investigate the statistic changes of blood lipids in 60 days. At the same time and condition,using rats and mice models for detecting the function of declining blood lipids food. Two kinds of health functioning foods are observed by detecting the level changes of different blood lipids on different kinds of models. ResultMice feed on high lipids food for 30 days can be used as hyperlipemia model. In 30 days continuing feeding,the high blood lipids level stays steadily. The level changes of three kinds of lipids selected for indicators between mice and rats models make no differences. Conclusion: It is possible,using mice instead of rats as a model for evaluating the function of declining high blood lipids food.

Key words: hyperlipemia mice model, functional food, declining blood lipids level

Wen-Jing, ZHANG Jing, Sang-Ting-Ting, Wang-Yan-Wei, Jiang-Ai. The Possibility of Using Hyperlipemia Mice as Model for Evaluating the Function of Declining Blood Lipids Food[J]. FOOD SCIENCE, 2006, 27(11): 479-482.

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The Possibility of Using Hyperlipemia Mice as Model for Evaluating the Function of Declining Blood Lipids Food

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