Abstract: To investigate the effects of lentinan on isolated skeletal muscular fatigue,we stimulated the isolated toad gastrocnemius by pulse electric curent. The results showed that: the lentinan at concentration of 0.03% ,0.09%,0.27% can prolong the time of contraction amplitude decreasing to 90%,50% and 10% of the max contraction amplitude (p<0.05). The lentinan at concentration of 0.81% can shorten the time of contraction amplitude decreasing to 50% and 10% of the max contraction amplitude (p<0.05). So the conclusion is that the proper concentration of lentinan has the effect of antifatigue.

Key words:  , lentinan； isolated toad gastrocnemius； fatigue；